Purpose: The LIGHTSITE I study investigated the efficacy and safety of photobiomodulation (PBM) treatment in subjects with dry age-related macular degeneration. Methods: Thirty subjects (46 eyes) were treated with the Valeda Light Delivery System, wherein subjects underwent two series of treatments (3× per week for 3–4 weeks) over 1 year. Outcome measures included best-corrected visual… Continue reading

Posted on August 22nd, 2019 in Research Articles | Comments Off on A DOUBLE-MASKED, RANDOMIZED, SHAM-CONTROLLED, SINGLE-CENTER STUDY WITH PHOTOBIOMODULATION FOR THE TREATMENT OF DRY AGE-RELATED MACULAR DEGENERATION

A pilot clinical study lead by LumiThera founders from The Toronto and Oak Ridge Study of Photobiomodulation (TORPA) looked at the effect of photobiomodulation (PBM) in the treatment of dry AMD. The TORPA data for dry AMD patient’s showed clinically and statistically significant improvement in both visual acuity and contrast sensitivity. TORPA Clinical Study The… Continue reading

Non-invasive photobiomodulation may help dry age-related macular degeneration by causing regression of drusen and improving retinal function with benefits in visual acuity and contrast sensitivity. By Lynda Charters; Reviewed by Graham Merry, MBBS, and Marion R. Munk, MD, PhD Photobiomodulation (PBM) may be a new non-invasive, light-based treatment for patients with dry age-related macular degeneration… Continue reading

Posted on September 22nd, 2016 in Research Articles | Comments Off on Dry AMD Therapy Evolves with Photobiomodulation

Clark E. Tedford,¹ Scott DeLapp,¹ Steven Jacques,² and Juanita Anders³ ¹LumiThera, Inc., Poulsbo, Washington 98370 ²Oregon Health and Science University, Portland, Oregon ³Department of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814 Background and Objective: Photobiomodulation (PBM) also known as low-level light therapy has been used successfully for the… Continue reading

Posted on May 7th, 2015 in Research Articles | Comments Off on Quantitative Analysis of Transcranial and Intraparenchymal Light Penetration in Human Cadaver Brain Tissue

Passarella S, Karu T. Institute of Laser and Information Technologies of the Russian Academy of Sciences, 142190 Troitsk, Moscow Region, Russian Federation. Abstract In addition to the major functions performed by in the cell, mitochondria play a major role in cell-light interaction. Accordingly it is generally accepted that mitochondria are crucial in cell photobiomodulation; however… Continue reading

Posted on October 1st, 2014 in Research Articles | Comments Off on Absorption of Monochromatic and Narrow Band Radiation in the Visible and Near IR by Both Mitochondrial and Non-Mitochondrial Photoacceptors Results in Photobiomodulation

Begum R, Powner MB, Hudson N, Hogg C, Jeffery G Institute of Ophthalmology, University College London, London, United Kingdom. Abstract Inflammation is an umbrella feature of ageing. It is present in the aged retina and many retinal diseases including age-related macular degeneration (AMD). In ageing and in AMD mitochondrial function declines. In normal ageing this… Continue reading

Posted on April 30th, 2014 in Research Articles | Comments Off on Treatment with 670 nm Light Upregulates Cytochrome C Oxidase Expression and Reduces Inflammation in an Age-Related Macular Degeneration Model

Gkotsi D, Begum R, Salt T, Lascaratos G, Hogg C, Chau KY, Schapira AH, Jeffery G. Institute of Ophthalmology, University College London, 11-43 Bath Street, London EC1V 9EL, UK. Moorfields Eye Hospital, UK. Institute of Neurology, University College London, UK. Institute of Ophthalmology, University College London, 11-43 Bath Street, London EC1V 9EL, UK. Abstract Progressive… Continue reading

Posted on April 30th, 2014 in Research Articles | Comments Off on Recharging Mitochondrial Batteries in Old Eyes. Near Infra-Red Increases ATP

Ivandic BT, Ivandic T. University of Heidelberg , Otto Meyerhof Centre, Heidelberg, Germany OBJECTIVE: This case report describes the effects of low-level laser therapy (LLLT) in a single patient with retinitis pigmentosa (RP). Background data: RP is a heritable disorder of the retina, which eventually leads to blindness. No therapy is currently available. METHODS: LLLT… Continue reading

Posted on April 30th, 2014 in Research Articles | Comments Off on Low-Level Laser Therapy Improves Vision in a Patient with Retinitis Pigmentosa

Tang J, Herda AA, Kern TS. Department of Ophthalmology, University of Kansas Medical Center, Prairie Village, Kansas, USA PURPOSE: Far-red/near-infrared phototherapy or photobiomodulation (PBM) has recently been reported to be an effective and non-invasive treatment method to inhibit lesions of diabetic retinopathy (DR) in animals. This study investigated the safety and efficacy of PBM in… Continue reading

Posted on April 30th, 2014 in Research Articles | Comments Off on Photobiomodulation in the Treatment of Patients with Non-Center-Involving Diabetic Macular Oedema

Natoli R, Valter K, Barbosa M, Dahlstrom J, Rutar M, Kent A, Provis J The John Curtin School of Medical Research, Australian National University, Canberra, Australian Capital Territory, Australia ; ARC Centre of Excellence in Vision Science, Australian National University, Canberra, Australian Capital Territory, Australia ; ANU Medical School, Australian National University, Canberra, Australian Capital… Continue reading

Posted on April 30th, 2014 in Research Articles | Comments Off on 670nm Photobiomodulation as a Novel Protection Against Retinopathy of Prematurity: Evidence from Oxygen Induced Retinopathy Models