Research Articles

Graham F. Merry,¹ Marion R. Munk,² Robert S. Dotson,¹ Michael G. Walker³ and Robert G. Devenyi⁴,⁵,⁶ ¹Photospectra Health Sciences, Toronto, Ontario, Canada ²Department of Ophthalmology, Inselspital University Hospital, Berne, Switzerland ³Walker Statistical Consulting, Carlsbad, California, USA ⁴Ophthalmologist in Chief and Director of Retinal Services, The Donald K. Johnson Eye Center, University Health Network, Toronto, Ontario,… Continue reading

Non-invasive photobiomodulation may help dry age-related macular degeneration by causing regression of drusen and improving retinal function with benefits in visual acuity and contrast sensitivity. By Lynda Charters; Reviewed by Graham Merry, MBBS, and Marion R. Munk, MD, PhD Photobiomodulation (PBM) may be a new non-invasive, light-based treatment for patients with dry age-related macular degeneration… Continue reading

Clark E. Tedford,¹ Scott DeLapp,¹ Steven Jacques,² and Juanita Anders³ ¹LumiThera, Inc., Poulsbo, Washington 98370 ²Oregon Health and Science University, Portland, Oregon ³Department of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814 Background and Objective: Photobiomodulation (PBM) also known as low-level light therapy has been used successfully for the… Continue reading

Passarella S, Karu T. Institute of Laser and Information Technologies of the Russian Academy of Sciences, 142190 Troitsk, Moscow Region, Russian Federation. Abstract In addition to the major functions performed by in the cell, mitochondria play a major role in cell-light interaction. Accordingly it is generally accepted that mitochondria are crucial in cell photobiomodulation; however… Continue reading

Begum R, Powner MB, Hudson N, Hogg C, Jeffery G Institute of Ophthalmology, University College London, London, United Kingdom. Abstract Inflammation is an umbrella feature of ageing. It is present in the aged retina and many retinal diseases including age-related macular degeneration (AMD). In ageing and in AMD mitochondrial function declines. In normal ageing this… Continue reading

Gkotsi D, Begum R, Salt T, Lascaratos G, Hogg C, Chau KY, Schapira AH, Jeffery G. Institute of Ophthalmology, University College London, 11-43 Bath Street, London EC1V 9EL, UK. Moorfields Eye Hospital, UK. Institute of Neurology, University College London, UK. Institute of Ophthalmology, University College London, 11-43 Bath Street, London EC1V 9EL, UK. Abstract Progressive… Continue reading

Ivandic BT, Ivandic T. University of Heidelberg , Otto Meyerhof Centre, Heidelberg, Germany OBJECTIVE: This case report describes the effects of low-level laser therapy (LLLT) in a single patient with retinitis pigmentosa (RP). Background data: RP is a heritable disorder of the retina, which eventually leads to blindness. No therapy is currently available. METHODS: LLLT… Continue reading

Tang J, Herda AA, Kern TS. Department of Ophthalmology, University of Kansas Medical Center, Prairie Village, Kansas, USA PURPOSE: Far-red/near-infrared phototherapy or photobiomodulation (PBM) has recently been reported to be an effective and non-invasive treatment method to inhibit lesions of diabetic retinopathy (DR) in animals. This study investigated the safety and efficacy of PBM in… Continue reading

Natoli R, Valter K, Barbosa M, Dahlstrom J, Rutar M, Kent A, Provis J The John Curtin School of Medical Research, Australian National University, Canberra, Australian Capital Territory, Australia ; ARC Centre of Excellence in Vision Science, Australian National University, Canberra, Australian Capital Territory, Australia ; ANU Medical School, Australian National University, Canberra, Australian Capital… Continue reading

Mii S, Kim C, Matsui H, Oharazawa H, Shi wa T, Takahashi H, Sakamoto A. Department of Anesthesiology, Nippon Medical School. Japan Abstract The authors applied near-infrared low-level laser irradiation (LLLI) directed to the stellate ganglion (SG) and to the common carotid artery (CCA), and compared the effects on central retinal artery blood flow using… Continue reading