Prevalence of type 1 (T1DM) and type 2 (T2DM) diabetes have reached a state of epidemic highs with the incidence of diabetes increasing at an alarming pace.1–4 Worldwide, diabetes is estimated to affect 463 million people and future estimates suggest an increase to 578 million by the year 2030.1 Diabetes can cause serious sight threatening… Continue reading
Photobiomodulation (PBM) refers to the process in which wavelengths of light are absorbed by intracellular photoacceptors, resulting in the activation of signaling pathways that culminate in biological changes within the cell. PBM is the result of low-intensity light-induced reactions in the cell in contrast to thermal photoablation produced by high-intensity lasers. PBM has been effectively… Continue reading
Purpose: The LIGHTSITE I study investigated the efficacy and safety of photobiomodulation (PBM) treatment in subjects with dry age-related macular degeneration. Methods: Thirty subjects (46 eyes) were treated with the Valeda Light Delivery System, wherein subjects underwent two series of treatments (3× per week for 3–4 weeks) over 1 year. Outcome measures included best-corrected visual… Continue reading
Doctors and patients have found this new mode of therapy beneficial. By Hakan Kaymak, MD; and Hartmut Schwahn, PhD The development of innovative treatments for debilitating diseases such as age-related macular degeneration (AMD) is crucial to advance patient care and to reduce burdens on patients, caregivers, and physicians. The dry, or nonexudative, form of AMD… Continue reading
Abstract The purpose of this protocol proposal is to suggest a new non-invasive combined therapeutic approach for dry age-related macular degeneration (AMD), an eye disease with no approved treatment or cure. A nutraceutical approach involving dietary supplementation of antioxidants can reduce its risk. Also, photobiomodulation (PBM, or LLLT) has shown promising results with the advantage… Continue reading
A pilot clinical study lead by LumiThera founders from The Toronto and Oak Ridge Study of Photobiomodulation (TORPA) looked at the effect of photobiomodulation (PBM) in the treatment of dry AMD. The TORPA data for dry AMD patient’s showed clinically and statistically significant improvement in both visual acuity and contrast sensitivity. TORPA Clinical Study The… Continue reading
Non-invasive photobiomodulation may help dry age-related macular degeneration by causing regression of drusen and improving retinal function with benefits in visual acuity and contrast sensitivity. By Lynda Charters; Reviewed by Graham Merry, MBBS, and Marion R. Munk, MD, PhD Photobiomodulation (PBM) may be a new non-invasive, light-based treatment for patients with dry age-related macular degeneration… Continue reading
Clark E. Tedford,¹ Scott DeLapp,¹ Steven Jacques,² and Juanita Anders³ ¹LumiThera, Inc., Poulsbo, Washington 98370 ²Oregon Health and Science University, Portland, Oregon ³Department of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814 Background and Objective: Photobiomodulation (PBM) also known as low-level light therapy has been used successfully for the… Continue reading
Passarella S, Karu T. Institute of Laser and Information Technologies of the Russian Academy of Sciences, 142190 Troitsk, Moscow Region, Russian Federation. Abstract In addition to the major functions performed by in the cell, mitochondria play a major role in cell-light interaction. Accordingly it is generally accepted that mitochondria are crucial in cell photobiomodulation; however… Continue reading
Begum R, Powner MB, Hudson N, Hogg C, Jeffery G Institute of Ophthalmology, University College London, London, United Kingdom. Abstract Inflammation is an umbrella feature of ageing. It is present in the aged retina and many retinal diseases including age-related macular degeneration (AMD). In ageing and in AMD mitochondrial function declines. In normal ageing this… Continue reading
